Nowadays, the effects of cannabinoids in humans are better known than in animals. Many studies have been done on rodents and other animals during the therapeutic researches for its use, there is still a small number of clinical trials speaking about the direct effects of cannabinoids in the rest of animals, mainly about CBD.
Where the studies have been primarily focused is in clearly understanding of the toxicity that THC represents in animals, as there exist differences in the receptors CB2. In the case of dogs, they have a bigger number of them and this is why the way of processing THC is so different, compared to that in human. From there, it is necessary to research what happens with the rest of animals and the existent differences in the Endocannabinoid System and how they assimilate cannabinoids or endocannabinoids, such as Anandamide, in order to have a better perspective of cannabinoids action.